1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Technology Analysis
3.8 Application Analysis
3.9 End User Analysis
3.10 Emerging Markets
3.11 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global In-vitro Toxicology Testing Market, By Product Type
5.1 Introduction
5.2 Software
5.3 Assay Kits
5.3.1 Enzyme Toxicity Assays
5.3.2 Receptor-Binding Assays
5.3.3 Tissue Culture Assays
5.3.4 Bacterial Toxicity Assays
5.3.5 Enzyme Toxicity Assays
5.3.6 Cell-based Elisa & Western Blots
5.4 Equipment
5.5 Consumables
5.6 Other Product Types
6 Global In-vitro Toxicology Testing Market, By Method
6.1 Introduction
6.2 Cellular Assay
6.2.1 High Throughput / High Content Screening
6.2.2 Molecular Imaging
6.2.3 Live Cells
6.2.4 Confocal Microscopy
6.2.5 Fixed Cells
6.3 In Silica
6.4 Biochemical Assay
7 Global In-vitro Toxicology Testing Market, By Technology
7.1 Introduction
7.2 Molecular Imaging
7.3 High Throughput Technology
7.4 Cell Culture Technology
7.5 OMICS Technology
7.6 Other Technologies
8 Global In-vitro Toxicology Testing Market, By Toxicity Endpoint & Test
8.1 Introduction
8.2 Genotoxicity
8.3 Cytotoxicity
8.4 Organ Toxicity
8.5 Phototoxicity
8.6 Dermal Toxicity
8.7 Kin irritation, Corrosion, & Sensitization
8.8 Absorption, Distribution, Metabolism, & Excretion
8.9 Other Toxicity Endpoint & Tests
9 Global In-vitro Toxicology Testing Market, By Application
9.1 Introduction
9.2 Endocrine Disruption
9.3 Systemic Toxicology
9.4 Occular Toxicity
9.5 Other Applications
10 Global In-vitro Toxicology Testing Market, By End User
10.1 Introduction
10.2 Pharmaceuticals Industry
10.3 Cosmetics and Households Products
10.4 Food Industry
10.5 Chemicals Industry
10.6 Diagnostics
10.7 Academic Institutes & Research Laboratories
10.8 Other End Users
11 Global In-vitro Toxicology Testing Market, By Geography
11.1 Introduction
11.2 North America
11.2.1 US
11.2.2 Canada
11.2.3 Mexico
11.3 Europe
11.3.1 Germany
11.3.2 UK
11.3.3 Italy
11.3.4 France
11.3.5 Spain
11.3.6 Rest of Europe
11.4 Asia Pacific
11.4.1 Japan
11.4.2 China
11.4.3 India
11.4.4 Australia
11.4.5 New Zealand
11.4.6 South Korea
11.4.7 Rest of Asia Pacific
11.5 South America
11.5.1 Argentina
11.5.2 Brazil
11.5.3 Chile
11.5.4 Rest of South America
11.6 Middle East & Africa
11.6.1 Saudi Arabia
11.6.2 UAE
11.6.3 Qatar
11.6.4 South Africa
11.6.5 Rest of Middle East & Africa
12 Key Developments
12.1 Agreements, Partnerships, Collaborations and Joint Ventures
12.2 Acquisitions & Mergers
12.3 New Product Launch
12.4 Expansions
12.5 Other Key Strategies
13 Company Profiling
13.1 Agilent Technologies
13.2 Abbott Laboratories
13.3 Covance
13.4 Bio-Rad Laboratories
13.5 GE Healthcare
13.6 Promega Corporation
13.7 Quest Diagnostics
13.8 Thermo Fisher Scientific
13.9 Merck KGaA
13.10 Eurofins Scientific
13.11 Evotec
13.12 Gentronix
13.13 BioIVT
13.14 Agilent Technologies
13.15 Catalent, Inc.
13.16 Thermo Fisher Scientific Inc.
13.17 Charles River
13.18 Helsinn Holding S.A.
13.19 Laboratory Corporation of America Holdings
13.20 Heron Therapeutics Inc,
List of Tables
Table 1 Global In-vitro Toxicology Testing Market Outlook, By Region (2021-2030) ($MN)
Table 2 Global In-vitro Toxicology Testing Market Outlook, By Product Type (2021-2030) ($MN)
Table 3 Global In-vitro Toxicology Testing Market Outlook, By Software (2021-2030) ($MN)
Table 4 Global In-vitro Toxicology Testing Market Outlook, By Assay Kits (2021-2030) ($MN)
Table 5 Global In-vitro Toxicology Testing Market Outlook, By Enzyme Toxicity Assays (2021-2030) ($MN)
Table 6 Global In-vitro Toxicology Testing Market Outlook, By Receptor-Binding Assays (2021-2030) ($MN)
Table 7 Global In-vitro Toxicology Testing Market Outlook, By Tissue Culture Assays (2021-2030) ($MN)
Table 8 Global In-vitro Toxicology Testing Market Outlook, By Bacterial Toxicity Assays (2021-2030) ($MN)
Table 9 Global In-vitro Toxicology Testing Market Outlook, By Enzyme Toxicity Assays (2021-2030) ($MN)
Table 10 Global In-vitro Toxicology Testing Market Outlook, By Cell-based Elisa & Western Blots (2021-2030) ($MN)
Table 11 Global In-vitro Toxicology Testing Market Outlook, By Equipment (2021-2030) ($MN)
Table 12 Global In-vitro Toxicology Testing Market Outlook, By Consumables (2021-2030) ($MN)
Table 13 Global In-vitro Toxicology Testing Market Outlook, By Other Product Types (2021-2030) ($MN)
Table 14 Global In-vitro Toxicology Testing Market Outlook, By Method (2021-2030) ($MN)
Table 15 Global In-vitro Toxicology Testing Market Outlook, By Cellular Assay (2021-2030) ($MN)
Table 16 Global In-vitro Toxicology Testing Market Outlook, By High Throughput / High Content Screening (2021-2030) ($MN)
Table 17 Global In-vitro Toxicology Testing Market Outlook, By Molecular Imaging (2021-2030) ($MN)
Table 18 Global In-vitro Toxicology Testing Market Outlook, By Live Cells (2021-2030) ($MN)
Table 19 Global In-vitro Toxicology Testing Market Outlook, By Confocal Microscopy (2021-2030) ($MN)
Table 20 Global In-vitro Toxicology Testing Market Outlook, By Fixed Cells (2021-2030) ($MN)
Table 21 Global In-vitro Toxicology Testing Market Outlook, By In Silica (2021-2030) ($MN)
Table 22 Global In-vitro Toxicology Testing Market Outlook, By Biochemical Assay (2021-2030) ($MN)
Table 23 Global In-vitro Toxicology Testing Market Outlook, By Technology (2021-2030) ($MN)
Table 24 Global In-vitro Toxicology Testing Market Outlook, By Molecular Imaging (2021-2030) ($MN)
Table 25 Global In-vitro Toxicology Testing Market Outlook, By High Throughput Technology (2021-2030) ($MN)
Table 26 Global In-vitro Toxicology Testing Market Outlook, By Cell Culture Technology (2021-2030) ($MN)
Table 27 Global In-vitro Toxicology Testing Market Outlook, By OMICS Technology (2021-2030) ($MN)
Table 28 Global In-vitro Toxicology Testing Market Outlook, By Other Technologies (2021-2030) ($MN)
Table 29 Global In-vitro Toxicology Testing Market Outlook, By Toxicity Endpoint & Test (2021-2030) ($MN)
Table 30 Global In-vitro Toxicology Testing Market Outlook, By Genotoxicity (2021-2030) ($MN)
Table 31 Global In-vitro Toxicology Testing Market Outlook, By Cytotoxicity (2021-2030) ($MN)
Table 32 Global In-vitro Toxicology Testing Market Outlook, By Organ Toxicity (2021-2030) ($MN)
Table 33 Global In-vitro Toxicology Testing Market Outlook, By Phototoxicity (2021-2030) ($MN)
Table 34 Global In-vitro Toxicology Testing Market Outlook, By Dermal Toxicity (2021-2030) ($MN)
Table 35 Global In-vitro Toxicology Testing Market Outlook, By Kin irritation, Corrosion, & Sensitization (2021-2030) ($MN)
Table 36 Global In-vitro Toxicology Testing Market Outlook, By Absorption, Distribution, Metabolism, & Excretion (2021-2030) ($MN)
Table 37 Global In-vitro Toxicology Testing Market Outlook, By Other Toxicity Endpoint & Tests (2021-2030) ($MN)
Table 38 Global In-vitro Toxicology Testing Market Outlook, By Application (2021-2030) ($MN)
Table 39 Global In-vitro Toxicology Testing Market Outlook, By Endocrine Disruption (2021-2030) ($MN)
Table 40 Global In-vitro Toxicology Testing Market Outlook, By Systemic Toxicology (2021-2030) ($MN)
Table 41 Global In-vitro Toxicology Testing Market Outlook, By Occular Toxicity (2021-2030) ($MN)
Table 42 Global In-vitro Toxicology Testing Market Outlook, By Other Applications (2021-2030) ($MN)
Table 43 Global In-vitro Toxicology Testing Market Outlook, By End User (2021-2030) ($MN)
Table 44 Global In-vitro Toxicology Testing Market Outlook, By Pharmaceuticals Industry (2021-2030) ($MN)
Table 45 Global In-vitro Toxicology Testing Market Outlook, By Cosmetics and Households Products (2021-2030) ($MN)
Table 46 Global In-vitro Toxicology Testing Market Outlook, By Food Industry (2021-2030) ($MN)
Table 47 Global In-vitro Toxicology Testing Market Outlook, By Chemicals Industry (2021-2030) ($MN)
Table 48 Global In-vitro Toxicology Testing Market Outlook, By Diagnostics (2021-2030) ($MN)
Table 49 Global In-vitro Toxicology Testing Market Outlook, By Academic Institutes & Research Laboratories (2021-2030) ($MN)
Table 50 Global In-vitro Toxicology Testing Market Outlook, By Other End Users (2021-2030) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
| ※参考情報 体外毒性試験とは、化学物質や製品の毒性を評価するために、動物以外の生物系を用いて行う実験手法のことを指します。具体的には、細胞株や組織片を使用して、物質が生体に与える影響を、実験室の環境下で調べます。このような試験は、新薬の開発や化学物質の安全性評価において、倫理的な観点やコストの面からもますます重要視されています。 体外毒性試験には、さまざまな種類があります。その一つは細胞毒性試験です。これは特定の細胞株に対して化学物質を添加し、細胞の生存率や増殖に与える影響を調べます。一般的な方法としては、MTTアッセイやLDHアッセイがあり、これらを用いて細胞の生存率を定量的に測定します。 次に、ゼブラフィッシュや線虫のようなモデル生物を用いた生体内毒性試験もあります。これらの生物はその発生過程が透明であるため、薬剤の影響を直接観察できる利点があります。また、これらの生物を使うことで、より複雑な生理的反応を探ることが可能になります。 さらに、オルガノイド技術を用いた試験も近年注目されています。オルガノイドは、特定の臓器の構造や機能を模した3次元細胞構造物です。これにより、より生理的な状態での毒性評価が可能となり、より臨床に即したデータを得ることができます。 体外毒性試験の用途は多岐にわたります。まず、医薬品の開発においては、新しい薬物候補の安全性を事前に評価し、動物実験に進む前に効果的なスクリーニングができます。これは、開発コストを抑えるうえでも非常に重要です。 また、化学物質のリスク評価にも頻繁に利用されます。特に化粧品や日用品に含まれる成分の安全性に関しては、動物実験を避ける動きが強まっているため、体外試験の重要性が増しています。さらには、環境中の化学物質の影響評価にも応用されます。 関連技術としては、細胞培養技術、マイクロ流体技術、人工知能（AI）を用いたデータ分析技術などが挙げられます。細胞培養技術は基本的なものであり、多種多様な細胞を取り扱う能力が求められます。マイクロ流体技術は、少量の試料で高精度な実験を可能にし、多様な試験を迅速に行う上で非常に役立ちます。 最近では、AIを用いたデータ解析が進展しており、大量の試験データを分析して毒性の予測を行うことが可能になっています。これにより、より効率的かつ効果的な毒性評価が実現されつつあります。 このように、体外毒性試験は、現代の生物医科学や環境科学の分野で非常に重要な役割を果たしています。科学技術の進展により、より高度な評価手法が継続的に開発されており、安全性評価の精度が向上しています。これにより、人や環境に対するリスクを低減し、より安全な製品の提供が可能になることが期待されています。体外毒性試験は今後ますますその重要性を増していくでしょう。 |
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