{"id":635934,"date":"2025-11-28T10:10:54","date_gmt":"2025-11-28T01:10:54","guid":{"rendered":"https:\/\/www.globalresearch.co.jp\/news\/?p=635934"},"modified":"2026-09-11T19:18:06","modified_gmt":"2026-09-11T10:18:06","slug":"%e3%80%8cmrna%e5%90%88%e6%88%90%e5%8e%9f%e6%96%99%e3%81%ae%e4%b8%96%e7%95%8c%e5%b8%82%e5%a0%b4%ef%bc%9a%e7%a8%ae%e9%a1%9e%e5%88%a5%ef%bc%88%e3%82%ad%e3%83%a3%e3%83%83%e3%83%97%e5%89%a4%e3%80%81","status":"publish","type":"post","link":"https:\/\/www.globalresearch.co.jp\/news\/635934\/","title":{"rendered":"\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u7523\u696d\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u3092\u8ca9\u58f2\u958b\u59cb"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>2025\u5e7411\u670828\u65e5<\/p>\n<p>H&amp;I\u30b0\u30ed\u30fc\u30d0\u30eb\u30ea\u30b5\u30fc\u30c1\uff08\u682a\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>*****\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u7523\u696d\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u3092\u8ca9\u58f2\u958b\u59cb *****<\/p>\n<p>&nbsp;<\/p>\n<p>H&amp;I\u30b0\u30ed\u30fc\u30d0\u30eb\u30ea\u30b5\u30fc\u30c1\u682a\u5f0f\u4f1a\u793e\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u4e2d\u592e\u533a\uff09\u306f\u3001\u3053\u306e\u5ea6\u3001Grand View Research\u793e\u304c\u8abf\u67fb\u30fb\u767a\u884c\u3057\u305f\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u5e02\u5834\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u306e\u8ca9\u58f2\u3092\u958b\u59cb\u3057\u307e\u3057\u305f\u3002mRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\u898f\u6a21\u3001\u5e02\u5834\u52d5\u5411\u3001\u5e02\u5834\u4e88\u6e2c\u3001\u95a2\u9023\u4f01\u696d\u60c5\u5831\u306a\u3069\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>***** \u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u306e\u6982\u8981 *****<\/p>\n<ol>\n<li><strong> \u5e02\u5834\u898f\u6a21\u3068\u4e88\u6e2c<\/strong><\/li>\n<\/ol>\n<p><strong>1-1. 2024\u5e74\u6642\u70b9\u306e\u5e02\u5834\u898f\u6a21<\/strong><\/p>\n<p><strong>\u4e16\u754c\u306e mRNA \u5408\u6210\u7528\u539f\u6750\u6599\u5e02\u5834\u306f\u30012024 \u5e74\u6642\u70b9\u3067 \u7d04 16.7 \u5104\u7c73\u30c9\u30eb \u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u308b\u3002<br \/>\n\u3053\u306e\u5e02\u5834\u306b\u306f\u3001mRNA \u3092\u4eba\u5de5\u7684\u306b\u8a2d\u8a08\u30fb\u5408\u6210\u3059\u308b\u969b\u306b\u4e0d\u53ef\u6b20\u306a\u5404\u7a2e\u539f\u6750\u6599\u304c\u542b\u307e\u308c\u308b\u3002\u4e3b\u306a\u539f\u6750\u6599\u306f\u4ee5\u4e0b\u306e\u3068\u304a\u308a\u3067\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff08\u4fee\u98fe\u578b\u30fb\u975e\u4fee\u98fe\u578b\u3092\u542b\u3080\uff09<\/strong><\/p>\n<p><strong>\u30ad\u30e3\u30c3\u30d4\u30f3\u30b0\u5264\uff08Cap1 \/ Cap2 \/ \u53cd\u8ee2\u30ad\u30e3\u30c3\u30d7\u306a\u3069\uff09<\/strong><\/p>\n<p><strong>\u30d7\u30e9\u30b9\u30df\u30c9 DNA\uff08\u30c6\u30f3\u30d7\u30ec\u30fc\u30c8 DNA\uff09<\/strong><\/p>\n<p><strong>\u5408\u6210\u9175\u7d20\uff08\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u3001\u30ad\u30e3\u30c3\u30d4\u30f3\u30b0\u9175\u7d20\u3001\u30e1\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc \u306a\u3069\uff09<\/strong><\/p>\n<p><strong>\u5404\u7a2e\u7de9\u885d\u6db2\u3001\u7cbe\u88fd\u95a2\u9023\u8a66\u85ac<\/strong><\/p>\n<p><strong>\u8102\u8cea\u95a2\u9023\u539f\u6599\uff08\u6700\u7d42\u88fd\u5264\u5411\u3051\uff09<\/strong><\/p>\n<p><strong>2020 \u5e74\u4ee5\u964d\u3001mRNA \u6280\u8853\u304c\u4e00\u6c17\u306b\u4e16\u754c\u7684\u306a\u8a8d\u77e5\u3092\u5f97\u305f\u3053\u3068\u304b\u3089\u3001\u3053\u308c\u3089\u306e\u539f\u6750\u6599\u306e\u5e02\u5834\u306f\u6025\u901f\u306a\u6210\u9577\u3092\u9042\u3052\u3066\u304d\u305f\u3002\u305d\u306e\u5f8c\u3001\u30ef\u30af\u30c1\u30f3\u9700\u8981\u306e\u4e00\u6642\u7684\u30d4\u30fc\u30af\u306f\u904e\u304e\u305f\u304c\u3001\u6cbb\u7642\u85ac\u30fb\u7814\u7a76\u7528\u9014\u306e\u62e1\u5927\u306b\u3088\u308a\u30012024 \u5e74\u306e\u6bb5\u968e\u3067\u3082\u4f9d\u7136\u9ad8\u3044\u9700\u8981\u304c\u7dad\u6301\u3055\u308c\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>1-2. \u4e88\u6e2c\u671f\u9593\u3068\u6210\u9577\u7387<\/strong><\/p>\n<p><strong>\u5e02\u5834\u306f 2025\u301c2030 \u5e74 \u306b\u304b\u3051\u3066 \u5e74\u5e73\u5747\u6210\u9577\u7387\uff08CAGR\uff09 5\u301c6% \u524d\u5f8c \u306e\u5b89\u5b9a\u7684\u306a\u62e1\u5927\u304c\u898b\u8fbc\u307e\u308c\u3066\u3044\u308b\u3002<br \/>\n2030 \u5e74\u306e\u5e02\u5834\u898f\u6a21\u306f \u7d04 23 \u5104\u7c73\u30c9\u30eb\u524d\u5f8c \u306b\u9054\u3059\u308b\u3068\u4e88\u6e2c\u3055\u308c\u3066\u304a\u308a\u3001\u77ed\u671f\u7684\u306a\u9700\u8981\u5909\u52d5\u304c\u3042\u308b\u3068\u306f\u3044\u3048\u3001\u9577\u671f\u7684\u306b\u306f\u7740\u5b9f\u306b\u62e1\u5927\u3059\u308b\u5e02\u5834\u3067\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>\u3053\u306e\u6210\u9577\u306b\u306f\u6b21\u306e\u3088\u3046\u306a\u80cc\u666f\u304c\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>\u65b0\u578b\u611f\u67d3\u75c7\u30ef\u30af\u30c1\u30f3\u306e\u7814\u7a76\u958b\u767a\u7d99\u7d9a<\/strong><\/p>\n<p><strong>\u304c\u3093\u9818\u57df\u306b\u304a\u3051\u308b\u6cbb\u7642\u7528 mRNA \u306e\u53f0\u982d<\/strong><\/p>\n<p><strong>\u5e0c\u5c11\u75be\u60a3\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u9818\u57df\u3067\u306e mRNA \u5fdc\u7528\u306e\u5e83\u304c\u308a<\/strong><\/p>\n<p><strong>\u7814\u7a76\u7528\u9014\u30fb\u30a2\u30ab\u30c7\u30df\u30a2\u304b\u3089\u306e\u9700\u8981\u7d99\u7d9a<\/strong><\/p>\n<p><strong>\u30d0\u30a4\u30aa\u533b\u85ac\u88fd\u9020\u306e\u81ea\u52d5\u5316\u30fb\u6a19\u6e96\u5316\u306e\u9032\u5c55<\/strong><\/p>\n<p><strong>\u5e02\u5834\u306f\u4e00\u6642\u671f\u306e\u6025\u62e1\u5927\u304b\u3089\u3001\u3088\u308a\u533b\u7642\u30a4\u30f3\u30d5\u30e9\u306b\u7d44\u307f\u8fbc\u307e\u308c\u305f\u201c\u7740\u5b9f\u306a\u6210\u9577\u6bb5\u968e\u201d\u3078\u3068\u79fb\u884c\u3057\u3064\u3064\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>1-3. \u5e02\u5834\u3092\u69cb\u6210\u3059\u308b\u4e3b\u8981\u30bb\u30b0\u30e1\u30f3\u30c8<\/strong><\/p>\n<p><strong>2024 \u5e74\u6642\u70b9\u3067\u5e02\u5834\u3092\u69cb\u6210\u3059\u308b\u4e3b\u306a\u30bb\u30b0\u30e1\u30f3\u30c8\u306f\u4ee5\u4e0b\u3067\u3042\u308b\u3002<\/strong><\/p>\n<ul>\n<li><strong> \u7a2e\u985e\u5225<\/strong><\/li>\n<\/ul>\n<p><strong>\u5e02\u5834\u6700\u5927\u306e\u30bb\u30b0\u30e1\u30f3\u30c8\u306f \u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff08NTP \/ \u4fee\u98fe NTP\uff09 \u3067\u3042\u308b\u3002mRNA \u5408\u6210\u5de5\u7a0b\u3067\u6700\u3082\u4f7f\u7528\u91cf\u304c\u591a\u304f\u3001\u9700\u8981\u306e\u5e95\u304c\u539a\u3044\u70b9\u304c\u7279\u5fb4\u3002<\/strong><\/p>\n<p><strong>\u305d\u306e\u4ed6\u306e\u539f\u6750\u6599\u3082\u91cd\u8981\u6027\u304c\u5897\u3057\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>\u30ad\u30e3\u30c3\u30d4\u30f3\u30b0\u5264\uff1a\u7ffb\u8a33\u52b9\u7387\u306b\u76f4\u7d50<\/strong><\/p>\n<p><strong>\u9175\u7d20\u985e\uff1a\u9ad8\u7d14\u5ea6\u30fb\u9ad8\u6d3b\u6027\u304c\u6c42\u3081\u3089\u308c\u308b<\/strong><\/p>\n<p><strong>\u30d7\u30e9\u30b9\u30df\u30c9 DNA\uff1a\u30c6\u30f3\u30d7\u30ec\u30fc\u30c8\u751f\u6210\u306e\u5fc5\u9808\u8981\u7d20<\/strong><\/p>\n<ul>\n<li><strong> \u7528\u9014\u5225<\/strong><\/li>\n<\/ul>\n<p><strong>\u6700\u3082\u5927\u304d\u306a\u7528\u9014\u306f \u30ef\u30af\u30c1\u30f3\u751f\u7523 \u3067\u3042\u308b\u3002<br \/>\n\u7d9a\u3044\u3066\u3001<\/strong><\/p>\n<p><strong>\u6cbb\u7642\u7528 mRNA<\/strong><\/p>\n<p><strong>\u7814\u7a76\u7528\u9014<\/strong><\/p>\n<p><strong>\u533b\u7642\u6a5f\u95a2\uff0f\u7814\u7a76\u6a5f\u95a2\u306b\u304a\u3051\u308b\u5c11\u91cf\u5408\u6210<br \/>\n\u306a\u3069\u304c\u4e3b\u6d41\u3002<\/strong><\/p>\n<ul>\n<li><strong> \u30a8\u30f3\u30c9\u30e6\u30fc\u30b6\u30fc\u5225<\/strong><\/li>\n<\/ul>\n<p><strong>\u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u4f01\u696d<\/strong><\/p>\n<p><strong>\u30ef\u30af\u30c1\u30f3\u30e1\u30fc\u30ab\u30fc<\/strong><\/p>\n<p><strong>\u53d7\u8a17\u88fd\u9020\u6a5f\u95a2\uff08CMO \/ CDMO\uff09<\/strong><\/p>\n<p><strong>\u53d7\u8a17\u7814\u7a76\u6a5f\u95a2\uff08CRO\uff09<\/strong><\/p>\n<p><strong>\u7814\u7a76\u6a5f\u95a2\uff08\u5927\u5b66\u30fb\u7814\u7a76\u6240\uff09<\/strong><\/p>\n<p><strong>\u30a8\u30f3\u30c9\u30e6\u30fc\u30b6\u30fc\u306e\u591a\u69d8\u5316\u306b\u3088\u308a\u3001\u4f4e\u5bb9\u91cf\u30fb\u9ad8\u7d14\u5ea6\u88fd\u54c1\u304b\u3089\u5927\u91cf\u751f\u7523\u5411\u3051 GMP \u30b0\u30ec\u30fc\u30c9\u539f\u6750\u6599\u307e\u3067\u3001\u591a\u5c64\u7684\u306a\u30cb\u30fc\u30ba\u304c\u5f62\u6210\u3055\u308c\u3066\u3044\u308b\u3002<\/strong><\/p>\n<ul>\n<li><strong> \u5730\u57df\u5225<\/strong><\/li>\n<\/ul>\n<p><strong>\u5317\u7c73\uff1a\u6700\u5927\u5e02\u5834\u3001\u7814\u7a76\u30fb\u751f\u7523\u62e0\u70b9\u304c\u591a\u3044<\/strong><\/p>\n<p><strong>\u6b27\u5dde\uff1a\u30d0\u30a4\u30aa\u533b\u85ac\u306e\u7814\u7a76\u958b\u767a\u304c\u76db\u3093<\/strong><\/p>\n<p><strong>\u30a2\u30b8\u30a2\u592a\u5e73\u6d0b\uff1a\u6700\u3082\u9ad8\u3044\u6210\u9577\u7387\u3001\u88fd\u9020\u62e0\u70b9\u306e\u62e1\u5927<\/strong><\/p>\n<p><strong>\u305d\u306e\u4ed6\u5730\u57df\uff1a\u533b\u7642\u30a2\u30af\u30bb\u30b9\u6539\u5584\u306b\u4f34\u3044\u9700\u8981\u5897\u52a0<\/strong><\/p>\n<p><strong>\u4ee5\u4e0a\u306e\u8981\u7d20\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001mRNA \u539f\u6750\u6599\u5e02\u5834\u306f\u591a\u69d8\u5316\u3057\u3001\u7814\u7a76\u30fb\u81e8\u5e8a\u30fb\u5546\u696d\u751f\u7523\u306e\u5404\u9818\u57df\u3067\u6210\u9577\u3057\u3066\u3044\u308b\u3002<\/strong><\/p>\n<ol start=\"2\">\n<li><strong> \u6210\u9577\u30c9\u30e9\u30a4\u30d0\u30fc\u3068\u5e02\u5834\u69cb\u9020<\/strong><\/li>\n<\/ol>\n<p><strong>2-1. mRNA \u6280\u8853\u306e\u666e\u53ca\u3068\u533b\u7642\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u306e\u52a0\u901f<\/strong><\/p>\n<p><strong>mRNA \u6280\u8853\u304c\u5e83\u304f\u8a8d\u77e5\u3055\u308c\u3001\u533b\u85ac\u54c1\u958b\u767a\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3068\u3057\u3066\u5b9a\u7740\u3057\u3064\u3064\u3042\u308b\u3053\u3068\u304c\u5e02\u5834\u306e\u6700\u5927\u306e\u6210\u9577\u8981\u56e0\u3067\u3042\u308b\u3002<\/strong><\/p>\n<ul>\n<li><strong> mRNA \u306f\u300c\u8a2d\u8a08\u304c\u901f\u3044\u300d<\/strong><\/li>\n<\/ul>\n<p><strong>\u75c5\u539f\u4f53\u3084\u304c\u3093\u6297\u539f\u306e\u914d\u5217\u3055\u3048\u5224\u660e\u3059\u308c\u3070\u3001\u77ed\u671f\u9593\u3067\u30ef\u30af\u30c1\u30f3\u5019\u88dc\u3092\u8a2d\u8a08\u3067\u304d\u308b\u3002\u3053\u306e\u8fc5\u901f\u6027\u306f\u5f93\u6765\u306e\u30ef\u30af\u30c1\u30f3\u6280\u8853\u306b\u306f\u306a\u3044\u5927\u304d\u306a\u5229\u70b9\u3002<\/strong><\/p>\n<ul>\n<li><strong> \u6cbb\u7642\u7528\u9014\u3078\u306e\u62e1\u5927<\/strong><\/li>\n<\/ul>\n<p><strong>\u611f\u67d3\u75c7\u3060\u3051\u3067\u306a\u304f\u3001\u4ee5\u4e0b\u306e\u5206\u91ce\u3067\u3082\u5fdc\u7528\u304c\u9032\u3080\u3002<\/strong><\/p>\n<p><strong>\u304c\u3093\u6cbb\u7642\uff08\u500b\u5225\u5316\u304c\u3093\u30ef\u30af\u30c1\u30f3\u306a\u3069\uff09<\/strong><\/p>\n<p><strong>\u907a\u4f1d\u6027\u75be\u60a3<\/strong><\/p>\n<p><strong>\u4ee3\u8b1d\u75be\u60a3<\/strong><\/p>\n<p><strong>\u5fc3\u8840\u7ba1\u75be\u60a3<\/strong><\/p>\n<p><strong>\u518d\u751f\u533b\u7642\u9818\u57df<\/strong><\/p>\n<p><strong>\u3053\u308c\u306b\u3088\u308a\u3001\u30ef\u30af\u30c1\u30f3\u4ee5\u5916\u306e\u5de8\u5927\u5e02\u5834\u304c\u5f62\u6210\u3055\u308c\u3064\u3064\u3042\u308a\u3001\u539f\u6750\u6599\u306e\u9700\u8981\u3082\u591a\u69d8\u306a\u7528\u9014\u306b\u5e83\u304c\u3063\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>2-2. \u7814\u7a76\u958b\u767a\u6295\u8cc7\u306e\u62e1\u5927<\/strong><\/p>\n<p><strong>\u4e16\u754c\u7684\u306b\u88fd\u85ac\u4f01\u696d\u3084\u30d0\u30a4\u30aa\u30c6\u30c3\u30af\u4f01\u696d\u3001\u30a2\u30ab\u30c7\u30df\u30a2\u3001\u653f\u5e9c\u7cfb\u6a5f\u95a2\u304c mRNA \u6280\u8853\u3078\u306e\u7814\u7a76\u958b\u767a\u6295\u8cc7\u3092\u5f37\u3081\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>\u5177\u4f53\u7684\u306a\u80cc\u666f\u306f\u6b21\u306e\u3068\u304a\u308a\u3002<\/strong><\/p>\n<p><strong>mRNA \u306e\u53ef\u80fd\u6027\u304c\u5b9f\u8a3c\u3055\u308c\u305f<\/strong><\/p>\n<p><strong>\u514d\u75ab\u5b66\u30fb\u907a\u4f1d\u5b66\u30fb\u6750\u6599\u79d1\u5b66\u306e\u767a\u5c55<\/strong><\/p>\n<p><strong>\u88fd\u9020\u6280\u8853\u306e\u5411\u4e0a<\/strong><\/p>\n<p><strong>\u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u5168\u4f53\u306e\u5e02\u5834\u62e1\u5927<\/strong><\/p>\n<p><strong>\u7814\u7a76\u6bb5\u968e\u3067\u5fc5\u8981\u3068\u3055\u308c\u308b\u300c\u9ad8\u7d14\u5ea6\u8a66\u85ac\u300d\u304b\u3089\u3001\u5546\u696d\u898f\u6a21\u3067\u5fc5\u8981\u3068\u3055\u308c\u308b\u300cGMP \u30b0\u30ec\u30fc\u30c9\u539f\u6750\u6599\u300d\u307e\u3067\u3001\u9700\u8981\u304c\u5c64\u3068\u3057\u3066\u5897\u52a0\u3057\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>2-3. \u30ef\u30af\u30c1\u30f3\u5e02\u5834\u306e\u7d99\u7d9a\u9700\u8981<\/strong><\/p>\n<p><strong>\u65b0\u578b\u611f\u67d3\u75c7\u5bfe\u5fdc\u306e\u7dca\u6025\u9700\u8981\u306f\u30d4\u30fc\u30af\u3092\u904e\u304e\u305f\u3082\u306e\u306e\u3001\u4ee5\u4e0b\u306e\u8981\u56e0\u306b\u3088\u308a\u30ef\u30af\u30c1\u30f3\u7528\u9014\u306f\u5f15\u304d\u7d9a\u304d\u5f37\u3044\u3002<\/strong><\/p>\n<p><strong>\u65b0\u305f\u306a\u30a6\u30a4\u30eb\u30b9\u5909\u7570\u3078\u306e\u5099\u3048<\/strong><\/p>\n<p><strong>\u5b63\u7bc0\u6027\u30ef\u30af\u30c1\u30f3\u3078\u306e\u5fdc\u7528<\/strong><\/p>\n<p><strong>\u65b0\u8208\u611f\u67d3\u75c7\u306b\u5bfe\u3059\u308b\u65e9\u671f\u5bfe\u5fdc<\/strong><\/p>\n<p><strong>\u30a2\u30b8\u30a2\u592a\u5e73\u6d0b\u5730\u57df\u3067\u306e\u9700\u8981\u5897<\/strong><\/p>\n<p><strong>\u7279\u306b\u516c\u7684\u6a5f\u95a2\u3084\u533b\u7642\u6a5f\u95a2\u306b\u3088\u308b\u5099\u84c4\u30fb\u8ffd\u52a0\u6295\u4e0e\u304c\u7d9a\u304f\u305f\u3081\u3001mRNA \u30d0\u30eb\u30af\u88fd\u9020\u3068\u539f\u6750\u6599\u9700\u8981\u306f\u4e00\u5b9a\u306e\u6c34\u6e96\u3092\u7dad\u6301\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/strong><\/p>\n<p><strong>2-4. \u4f9b\u7d66\u30c1\u30a7\u30fc\u30f3\u306e\u9ad8\u5ea6\u5316\u3068\u54c1\u8cea\u8981\u6c42<\/strong><\/p>\n<p><strong>mRNA \u539f\u6750\u6599\u306f\u3001\u88fd\u9020\u30d7\u30ed\u30bb\u30b9\u304c\u9ad8\u5ea6\u3067\u3042\u308a\u3001\u88fd\u85ac\u7528\u9014\u3067\u306f\u7279\u306b\u4ee5\u4e0b\u304c\u6c42\u3081\u3089\u308c\u308b\u3002<\/strong><\/p>\n<p><strong>\u8d85\u9ad8\u7d14\u5ea6<\/strong><\/p>\n<p><strong>RNase \u6c5a\u67d3\u306e\u5b8c\u5168\u6392\u9664<\/strong><\/p>\n<p><strong>GMP \u5b8c\u5168\u6e96\u62e0<\/strong><\/p>\n<p><strong>\u30c8\u30ec\u30fc\u30b5\u30d3\u30ea\u30c6\u30a3<\/strong><\/p>\n<p><strong>\u5b89\u5b9a\u4f9b\u7d66\u80fd\u529b<\/strong><\/p>\n<p><strong>\u30ed\u30c3\u30c8\u3054\u3068\u306e\u5747\u4e00\u6027<\/strong><\/p>\n<p><strong>\u898f\u5236\u57fa\u6e96\u306e\u9075\u5b88<\/strong><\/p>\n<p><strong>\u3053\u308c\u306b\u3088\u308a\u3001\u539f\u6750\u6599\u5e02\u5834\u306f\u5358\u306a\u308b\u5316\u5b66\u8a66\u85ac\u5e02\u5834\u3067\u306f\u306a\u304f\u3001\u300c\u9ad8\u4ed8\u52a0\u4fa1\u5024\u30d0\u30a4\u30aa\u539f\u6599\u5e02\u5834\u300d\u3068\u3057\u3066\u78ba\u7acb\u3055\u308c\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>2-5. \u5730\u57df\u5225\u3067\u7570\u306a\u308b\u6210\u9577\u52d5\u5411<\/strong><\/p>\n<ul>\n<li><strong> \u5317\u7c73<\/strong><\/li>\n<\/ul>\n<p><strong>\u7814\u7a76\u6a5f\u95a2\u30fb\u88fd\u85ac\u4f01\u696d\u304c\u96c6\u4e2d<\/strong><\/p>\n<p><strong>CMO\/CDMO \u306e\u751f\u7523\u62e1\u5927<\/strong><\/p>\n<p><strong>\u6280\u8853\u958b\u767a\u304c\u65e9\u3044<\/strong><\/p>\n<p><strong>\u533b\u7642\u6295\u8cc7\u984d\u304c\u5927\u304d\u3044<\/strong><\/p>\n<ul>\n<li><strong> \u6b27\u5dde<\/strong><\/li>\n<\/ul>\n<p><strong>\u898f\u5236\u5236\u5ea6\u304c\u6574\u5099\u3055\u308c\u88fd\u9020\u57fa\u6e96\u304c\u9ad8\u3044<\/strong><\/p>\n<p><strong>\u30d0\u30a4\u30aa\u533b\u85ac\u7523\u696d\u304c\u6210\u719f<\/strong><\/p>\n<p><strong>\u56fd\u5883\u3092\u8d85\u3048\u305f\u5171\u540c\u7814\u7a76\u304c\u76db\u3093<\/strong><\/p>\n<ul>\n<li><strong> \u30a2\u30b8\u30a2\u592a\u5e73\u6d0b<\/strong><\/li>\n<\/ul>\n<p><strong>\u9700\u8981\u62e1\u5927\u30fb\u88fd\u9020\u6295\u8cc7\u306e\u5897\u52a0<\/strong><\/p>\n<p><strong>\u5927\u898f\u6a21\u751f\u7523\u62e0\u70b9\u306e\u8a2d\u7acb\u304c\u52a0\u901f<\/strong><\/p>\n<p><strong>\u4e2d\u56fd\u30fb\u65e5\u672c\u30fb\u97d3\u56fd\u30fb\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u306a\u3069\u3067\u5e02\u5834\u6210\u9577\u304c\u9855\u8457<\/strong><\/p>\n<p><strong>\u4e16\u754c\u5e02\u5834\u306e\u91cd\u5fc3\u306f\u5f90\u3005\u306b\u30a2\u30b8\u30a2\u5730\u57df\u306b\u3082\u5e83\u304c\u308a\u3064\u3064\u3042\u308b\u3002<\/strong><\/p>\n<ol start=\"3\">\n<li><strong> \u8ab2\u984c\u30fb\u30ea\u30b9\u30af\u3068\u5c06\u6765\u5c55\u671b<\/strong><\/li>\n<\/ol>\n<p><strong>3-1. \u539f\u6750\u6599\u4f9b\u7d66\u306e\u5236\u7d04<\/strong><\/p>\n<p><strong>mRNA \u5408\u6210\u539f\u6750\u6599\u306f\u88fd\u9020\u96e3\u5ea6\u304c\u9ad8\u304f\u3001\u4f9b\u7d66\u80fd\u529b\u304c\u5e02\u5834\u306e\u6210\u9577\u306b\u8ffd\u3044\u3064\u304b\u306a\u3044\u30ea\u30b9\u30af\u304c\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>\u88fd\u9020\u8a2d\u5099\u306e\u62e1\u5f35\u306b\u9ad8\u30b3\u30b9\u30c8\u304c\u304b\u304b\u308b<\/strong><\/p>\n<p><strong>\u9ad8\u7d14\u5ea6\u6761\u4ef6\u306e\u7dad\u6301\u304c\u96e3\u3057\u3044<\/strong><\/p>\n<p><strong>\u4e16\u754c\u540c\u6642\u9700\u8981\u304c\u767a\u751f\u3059\u308b\u3068\u4f9b\u7d66\u4e0d\u8db3\u306b\u306a\u308a\u3084\u3059\u3044<\/strong><\/p>\n<p><strong>\u7279\u306b\u3001\u9175\u7d20\u3084\u4fee\u98fe\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306a\u3069\u9ad8\u5ea6\u306a\u539f\u6599\u306f\u751f\u7523\u3067\u304d\u308b\u4f01\u696d\u304c\u9650\u3089\u308c\u3066\u304a\u308a\u3001\u30b5\u30d7\u30e9\u30a4\u30c1\u30a7\u30fc\u30f3\u306e\u8106\u5f31\u6027\u304c\u4f9d\u7136\u3068\u3057\u3066\u8ab2\u984c\u3067\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>3-2. \u751f\u7523\u30b3\u30b9\u30c8\u3068\u4fa1\u683c\u7af6\u4e89\u306e\u9ad8\u307e\u308a<\/strong><\/p>\n<p><strong>\u5e02\u5834\u304c\u6210\u9577\u3059\u308b\u4e00\u65b9\u3067\u3001\u4f01\u696d\u9593\u7af6\u4e89\u304c\u6fc0\u5316\u3059\u308b\u3068\u3001\u4ee5\u4e0b\u306e\u8ab2\u984c\u304c\u751f\u3058\u308b\u3002<\/strong><\/p>\n<p><strong>\u9ad8\u54c1\u8cea\u3092\u7dad\u6301\u3057\u3064\u3064\u30b3\u30b9\u30c8\u524a\u6e1b\u3059\u308b\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc<\/strong><\/p>\n<p><strong>\u533b\u85ac\u54c1\u30e1\u30fc\u30ab\u30fc\u304b\u3089\u306e\u4fa1\u683c\u5f15\u304d\u4e0b\u3052\u8981\u6c42<\/strong><\/p>\n<p><strong>\u30aa\u30da\u30ec\u30fc\u30b7\u30e7\u30f3\u30b3\u30b9\u30c8\u306e\u5897\u52a0\uff08\u54c1\u8cea\u7ba1\u7406\u3001\u4eba\u6750\u78ba\u4fdd\u306a\u3069\uff09<\/strong><\/p>\n<p><strong>\u5e02\u5834\u306e\u6210\u719f\u306b\u3068\u3082\u306a\u3044\u3001\u54c1\u8cea\u00d7\u4fa1\u683c\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u91cd\u8981\u306b\u306a\u308b\u3002<\/strong><\/p>\n<p><strong>3-3. \u54c1\u8cea\u304a\u3088\u3073\u898f\u5236\u3078\u306e\u9ad8\u5ea6\u5bfe\u5fdc<\/strong><\/p>\n<p><strong>mRNA \u306e\u533b\u7642\u7528\u9014\u3067\u306f\u3001\u539f\u6750\u6599\u6bb5\u968e\u304b\u3089\u53b3\u683c\u306a\u898f\u5236\u304c\u9069\u7528\u3055\u308c\u308b\u3002<\/strong><\/p>\n<p><strong>\u5404\u56fd\u306e GMP \u57fa\u6e96\u306e\u9055\u3044<\/strong><\/p>\n<p><strong>\u6587\u66f8\u5316\u3001\u30c8\u30ec\u30fc\u30b5\u30d3\u30ea\u30c6\u30a3\u306e\u5fb9\u5e95<\/strong><\/p>\n<p><strong>\u6bce\u30ed\u30c3\u30c8\u306e\u691c\u67fb\u30fb\u8a3c\u660e\u66f8\u306e\u767a\u884c<\/strong><\/p>\n<p><strong>\u5909\u66f4\u7ba1\u7406\u30fb\u5b89\u5b9a\u6027\u8a66\u9a13\u306e\u7fa9\u52d9<\/strong><\/p>\n<p><strong>\u898f\u5236\u5bfe\u5fdc\u306e\u8ca0\u62c5\u306f\u5927\u304d\u304f\u3001\u6280\u8853\u30fb\u4eba\u6750\u30fb\u8a2d\u5099\u306b\u5bfe\u3059\u308b\u6295\u8cc7\u304c\u6c42\u3081\u3089\u308c\u308b\u3002<\/strong><\/p>\n<p><strong>3-4. \u5e02\u5834\u9700\u8981\u306e\u5909\u52d5\u30ea\u30b9\u30af<\/strong><\/p>\n<p><strong>\u9700\u8981\u306f\u6210\u9577\u3057\u3066\u3044\u308b\u304c\u3001\u4ee5\u4e0b\u306e\u5909\u52d5\u8981\u56e0\u304c\u5b58\u5728\u3059\u308b\u3002<\/strong><\/p>\n<p><strong>\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u5f8c\u306e\u30ef\u30af\u30c1\u30f3\u9700\u8981\u306e\u6ce2<\/strong><\/p>\n<p><strong>\u65b0\u898f\u6cbb\u7642\u85ac\u306e\u627f\u8a8d\u6642\u671f\u306e\u9045\u308c<\/strong><\/p>\n<p><strong>\u7814\u7a76\u958b\u767a\u306e\u6210\u5426<\/strong><\/p>\n<p><strong>\u653f\u7b56\u30fb\u898f\u5236\u306e\u5909\u5316<\/strong><\/p>\n<p><strong>\u539f\u6750\u6599\u4fa1\u683c\u306e\u5909\u52d5<\/strong><\/p>\n<p><strong>\u7279\u306b\u30ef\u30af\u30c1\u30f3\u9818\u57df\u3067\u306f\u3001\u4e00\u6642\u7684\u306a\u9700\u8981\u4e0a\u6607\u3068\u4e0b\u964d\u304c\u7e70\u308a\u8fd4\u3055\u308c\u3084\u3059\u3044\u3002<\/strong><\/p>\n<p><strong>3-5. \u7af6\u4e89\u74b0\u5883\u306e\u6fc0\u5316\u3068\u53c2\u5165\u969c\u58c1<\/strong><\/p>\n<p><strong>\u9ad8\u5ea6\u306a\u539f\u6750\u6599\u307b\u3069\u53c2\u5165\u969c\u58c1\u304c\u9ad8\u304f\u3001\u65e2\u5b58\u4f01\u696d\u306e\u512a\u4f4d\u6027\u304c\u5f37\u3044\u3002<\/strong><\/p>\n<p><strong>\u9ad8\u5ea6\u306a\u6280\u8853\u30fb\u8a2d\u5099\u6295\u8cc7\u304c\u5fc5\u8981<\/strong><\/p>\n<p><strong>GMP \u5bfe\u5fdc\u3067\u30b3\u30b9\u30c8\u5897<\/strong><\/p>\n<p><strong>\u4fe1\u983c\u6027\u30fb\u5b9f\u7e3e\u304c\u91cd\u8996\u3055\u308c\u308b\u305f\u3081\u65b0\u898f\u53c2\u5165\u304c\u96e3\u3057\u3044<\/strong><\/p>\n<p><strong>\u4e00\u65b9\u3001\u65e2\u5b58\u4f01\u696d\u9593\u3067\u306f\u7af6\u4e89\u304c\u6fc0\u5316\u3059\u308b\u305f\u3081\u3001\u5dee\u5225\u5316\u6226\u7565\u304c\u5fc5\u8981\u3068\u306a\u308b\u3002<\/strong><\/p>\n<ol start=\"4\">\n<li><strong> \u7dcf\u62ec\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/li>\n<\/ol>\n<p><strong>mRNA \u5408\u6210\u7528\u539f\u6750\u6599\u5e02\u5834\u306f\u3001\u30ef\u30af\u30c1\u30f3\u7528\u9014\u3092\u4e2d\u5fc3\u306b\u6025\u901f\u306b\u62e1\u5927\u3057\u3001\u73fe\u5728\u306f\u6cbb\u7642\u7528\u9014\u3084\u7814\u7a76\u7528\u9014\u306b\u5e02\u5834\u304c\u5e83\u304c\u308a\u3064\u3064\u3042\u308b\u3002<br \/>\n2024 \u5e74\u6642\u70b9\u3067\u7d04 16.7 \u5104\u7c73\u30c9\u30eb\u30012030 \u5e74\u306b\u306f 23 \u5104\u7c73\u30c9\u30eb\u524d\u5f8c\u3068\u3044\u3046\u4e88\u6e2c\u306f\u3001\u77ed\u671f\u306e\u5909\u52d5\u3092\u542b\u307f\u3064\u3064\u3082\u9577\u671f\u7684\u306a\u5b89\u5b9a\u6210\u9577\u3092\u793a\u3057\u3066\u3044\u308b\u3002<\/strong><\/p>\n<p><strong>\u5e02\u5834\u62e1\u5927\u306e\u80cc\u666f\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>mRNA \u6280\u8853\u306e\u533b\u7642\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u5316<\/strong><\/p>\n<p><strong>\u6cbb\u7642\u7528\u9014\u306e\u672c\u683c\u7684\u306a\u5b9f\u7528\u5316<\/strong><\/p>\n<p><strong>\u5404\u56fd\u306e\u7814\u7a76\u958b\u767a\u6295\u8cc7\u306e\u5897\u52a0<\/strong><\/p>\n<p><strong>\u9ad8\u4ed8\u52a0\u4fa1\u5024\u539f\u6750\u6599\u306e\u9700\u8981\u62e1\u5927<\/strong><\/p>\n<p><strong>\u30a2\u30b8\u30a2\u5730\u57df\u3067\u306e\u9700\u8981\u6210\u9577<\/strong><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p>***** \u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u306e\u76ee\u6b21(\u4e00\u90e8\u629c\u7c8b) *****<\/p>\n<p><strong>\u7b2c1\u7ae0\u3000\u306f\u3058\u3081\u306b \u2014 \u30ec\u30dd\u30fc\u30c8\u6982\u8981\u3068\u76ee\u7684<\/strong><\/p>\n<p><strong>1.1 \u30ec\u30dd\u30fc\u30c8\u306e\u80cc\u666f\u304a\u3088\u3073\u76ee\u7684<br \/>\n1.2 mRNA \u6280\u8853\u306e\u9032\u5316\u3068\u5e02\u5834\u52d5\u5411<br \/>\n1.3 \u5bfe\u8c61\u7bc4\u56f2\u304a\u3088\u3073\u5b9a\u7fa9<br \/>\n1.3.1 \u201cmRNA \u5408\u6210\u7528\u539f\u6750\u6599\u201d\u306e\u5b9a\u7fa9\uff08\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30ad\u30e3\u30c3\u30d4\u30f3\u30b0\u5264\u3001\u9175\u7d20\u3001\u30c6\u30f3\u30d7\u30ec\u30fc\u30c8 DNA \u306a\u3069\uff09<br \/>\n1.3.2 \u201c\u7528\u9014\uff0f\u30a8\u30f3\u30c9\u30e6\u30fc\u30b6\u30fc\uff0f\u30b0\u30ec\u30fc\u30c9\u201d \u306b\u3088\u308b\u5206\u985e\u57fa\u6e96<br \/>\n1.4 \u8abf\u67fb\u5bfe\u8c61\u306e\u5730\u7406\u7684\u7bc4\u56f2\u3068\u671f\u9593<br \/>\n1.5 \u30ec\u30dd\u30fc\u30c8\u306e\u69cb\u6210\u6982\u8981<\/strong><\/p>\n<p><strong>\u7b2c2\u7ae0\u3000\u8abf\u67fb\u624b\u6cd5\u3068\u60f3\u5b9a\u4eee\u5b9a<\/strong><\/p>\n<p><strong>2.1 \u30c7\u30fc\u30bf\u53ce\u96c6\u65b9\u6cd5<br \/>\n2.1.1 \u516c\u7684\u30c7\u30fc\u30bf\u3001\u696d\u754c\u30c7\u30fc\u30bf\u3001\u6587\u732e\u30ec\u30d3\u30e5\u30fc<br \/>\n2.1.2 \u4f01\u696d\u8cc7\u6599\u3001\u696d\u754c\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u3001\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u8abf\u67fb<br \/>\n2.2 \u30e2\u30c7\u30eb\u304a\u3088\u3073\u5206\u6790\u624b\u6cd5<br \/>\n2.2.1 \u6b74\u53f2\u30c7\u30fc\u30bf\u5206\u6790<br \/>\n2.2.2 \u4e88\u6e2c\u30e2\u30c7\u30eb\u3068\u524d\u63d0\u6761\u4ef6<br \/>\n2.3 \u30bb\u30b0\u30e1\u30f3\u30c6\u30fc\u30b7\u30e7\u30f3\u306e\u5b9a\u7fa9\u3068\u5206\u985e\u67a0\u7d44\u307f<br \/>\n2.4 \u30ec\u30dd\u30fc\u30c8\u306e\u5236\u7d04\u4e8b\u9805\u3068\u6ce8\u610f\u70b9<\/strong><\/p>\n<p><strong>\u7b2c3\u7ae0\u3000\u5e02\u5834\u30b5\u30de\u30ea\u30fc &amp; \u30de\u30af\u30ed\u30c8\u30ec\u30f3\u30c9<\/strong><\/p>\n<p><strong>3.1 \u5e02\u5834\u898f\u6a21\u3068\u6210\u9577\u898b\u901a\u3057\u306e\u30b5\u30de\u30ea\u30fc\uff08\u904e\u53bb \u2192 \u4e88\u6e2c\u5024\uff09<br \/>\n3.2 mRNA \u6280\u8853\u306e\u666e\u53ca\u80cc\u666f\u3068\u5fdc\u7528\u62e1\u5927<br \/>\n3.3 \u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u30d0\u30a4\u30aa\u533b\u85ac\u30fb\u30ef\u30af\u30c1\u30f3\u7523\u696d\u306e\u5909\u5316<br \/>\n3.4 \u898f\u5236\u52d5\u5411\u30fb\u54c1\u8cea\u57fa\u6e96\u3068 GMP\uff0fGSP \u57fa\u6e96\u306e\u91cd\u8981\u6027<br \/>\n3.5 \u30b5\u30d7\u30e9\u30a4\u30c1\u30a7\u30fc\u30f3\u69cb\u9020\u306e\u5909\u5316\u3068\u539f\u6750\u6599\u4f9b\u7d66\u306e\u8ab2\u984c<\/strong><\/p>\n<p><strong>\u7b2c4\u7ae0\u3000\u88fd\u54c1\u30bf\u30a4\u30d7\u5225\u5206\u6790\uff08\u539f\u6750\u6599\u30bf\u30a4\u30d7\u5225\uff09<\/strong><\/p>\n<p><strong>4.1 \u30bf\u30a4\u30d7\u5225\u5e02\u5834\u69cb\u9020 \u2014 \u6982\u8981<br \/>\n4.2 \u30ad\u30e3\u30c3\u30d4\u30f3\u30b0\u5264\uff08Capping Agents\uff09<br \/>\n4.2.1 \u30b5\u30d6\u30bf\u30a4\u30d7\u5225\u5206\u985e\uff08\u4f8b\uff1aARCA\u3001CleanCap\u3001\u9175\u7d20\u30ad\u30e3\u30c3\u30d7\u306a\u3069\uff09<br \/>\n4.2.2 \u5e02\u5834\u30b7\u30a7\u30a2\u3068\u6210\u9577\u4e88\u6e2c<br \/>\n4.2.3 \u6280\u8853\u30c8\u30ec\u30f3\u30c9\u3068\u54c1\u8cea\u8981\u4ef6\uff08\u7ffb\u8a33\u52b9\u7387\u3001\u514d\u75ab\u539f\u6027\u4f4e\u6e1b\u306a\u3069\uff09<\/strong><\/p>\n<p><strong>4.3 \u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff08Nucleotides\uff09<br \/>\n4.3.1 \u4fee\u98fe\u30cc\u30af\u30ec\u30aa\u30c1\u30c9 vs \u901a\u5e38\u30cc\u30af\u30ec\u30aa\u30c1\u30c9<br \/>\n4.3.2 \u5404\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306e\u9700\u8981\u52d5\u5411<br \/>\n4.3.3 \u4f9b\u7d66\u30fb\u30b3\u30b9\u30c8\u30fb\u54c1\u8cea\u7ba1\u7406\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/p>\n<p><strong>4.4 \u30d7\u30e9\u30b9\u30df\u30c9 DNA\uff08\u30c6\u30f3\u30d7\u30ec\u30fc\u30c8 DNA\uff09<br \/>\n4.4.1 DNA \u30c6\u30f3\u30d7\u30ec\u30fc\u30c8\u306e\u5f79\u5272\u3068\u91cd\u8981\u6027<br \/>\n4.4.2 \u30b5\u30d7\u30e9\u30a4\u72b6\u6cc1\u3068\u5e02\u5834\u6a5f\u4f1a<\/strong><\/p>\n<p><strong>4.5 \u9175\u7d20\u304a\u3088\u3073\u9175\u7d20\u95a2\u9023\u8a66\u85ac\uff08RNA \u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u3001RNase \u963b\u5bb3\u5264\u3001\u30af\u30ea\u30fc\u30f3\u30a2\u30c3\u30d7\u9175\u7d20\u306a\u3069\uff09<br \/>\n4.5.1 \u4e3b\u306a\u9175\u7d20\u306e\u5206\u985e<br \/>\n4.5.2 GMP\uff0f\u7814\u7a76\u7528\u9014\u5225\u306e\u63d0\u4f9b\u5f62\u614b<br \/>\n4.5.3 \u9700\u8981\u52d5\u5411\u3068\u6210\u9577\u8a08\u753b<\/strong><\/p>\n<p><strong>4.6 \u305d\u306e\u4ed6\u539f\u6750\u6599\u304a\u3088\u3073\u88dc\u52a9\u8a66\u85ac\uff08\u7cbe\u88fd\u30ad\u30c3\u30c8\u3001\u6eb6\u5a92\u3001\u30d0\u30c3\u30d5\u30a1\u30fc\u3001\u8102\u8cea\uff0fLNP \u95a2\u9023\u306a\u3069\uff09<br \/>\n4.6.1 \u88fd\u5264\u5f62\u6210\u306b\u95a2\u3059\u308b\u6750\u6599\u9700\u8981<br \/>\n4.6.2 \u54c1\u8cea\u7ba1\u7406\u30fb\u5206\u6790\u6750\u6599\u306e\u9700\u8981\u52d5\u5411<\/strong><\/p>\n<p><strong>4.7 \u30bf\u30a4\u30d7\u5225\u5408\u8a08\u5e02\u5834\u898f\u6a21\u3068\u4e88\u6e2c \u2014 2021\u20132024 \u5b9f\u7e3e\u304a\u3088\u3073 2025\u20132034 \u4e88\u6e2c<\/strong><\/p>\n<p><strong>\u7b2c5\u7ae0\u3000\u30b0\u30ec\u30fc\u30c9\u5225\u5e02\u5834\u5206\u6790<\/strong><\/p>\n<p><strong>5.1 \u30b0\u30ec\u30fc\u30c9\u533a\u5206\u6982\u89b3\uff08\u7814\u7a76\u7528\u8a66\u85ac vs GMP \u30b0\u30ec\u30fc\u30c9\uff09<br \/>\n5.2 \u7814\u7a76\u7528\u8a66\u85ac\u5e02\u5834\u306e\u69cb\u9020\u3068\u7528\u9014\uff08\u7814\u7a76\u6a5f\u95a2\u3001\u30a2\u30ab\u30c7\u30df\u30a2\u3001\u521d\u671f\u958b\u767a\u6bb5\u968e\uff09<br \/>\n5.3 GMP \u30b0\u30ec\u30fc\u30c9\u5e02\u5834\u306e\u69cb\u9020\u3068\u7528\u9014\uff08\u88fd\u85ac\u4f01\u696d\u3001CDMO\uff0fCMO\u3001\u5546\u696d\u533b\u85ac\u30fb\u30ef\u30af\u30c1\u30f3\u751f\u7523\uff09<br \/>\n5.4 \u30b0\u30ec\u30fc\u30c9\u5225\u30b7\u30a7\u30a2\u3068\u6210\u9577\u4e88\u6e2c<br \/>\n5.5 \u54c1\u8cea\u7ba1\u7406\u30fb\u898f\u5236\u9075\u5b88\u306e\u8981\u4ef6\u3068\u696d\u754c\u306e\u53d6\u7d44\u307f<\/strong><\/p>\n<p><strong>\u7b2c6\u7ae0\u3000\u7528\u9014\u5225\u5e02\u5834\u5206\u6790<\/strong><\/p>\n<p><strong>6.1 \u7528\u9014\u30bb\u30b0\u30e1\u30f3\u30c8\u306e\u5b9a\u7fa9<br \/>\n6.1.1 \u30ef\u30af\u30c1\u30f3\u751f\u7523\u7528\u9014<br \/>\n6.1.2 \u6cbb\u7642\u7528 mRNA\uff08\u533b\u85ac\u54c1\uff09\u751f\u7523\u7528\u9014<br \/>\n6.1.3 \u7814\u7a76\u7528\u9014\u304a\u3088\u3073\u8a3a\u65ad\uff0f\u958b\u767a\u7528\u9014<\/strong><\/p>\n<p><strong>6.2 \u5404\u7528\u9014\u306e\u5e02\u5834\u898f\u6a21\u3068\u30b7\u30a7\u30a2\uff082024 \u5e74\u6642\u70b9\uff09<br \/>\n6.3 \u7528\u9014\u5225\u6210\u9577\u30c8\u30ec\u30f3\u30c9\u3068\u4e88\u6e2c\uff082025\u20132034 \u5e74\uff09<br \/>\n6.4 \u7528\u9014\u5225\u306e\u7279\u6027\uff1a\u54c1\u8cea\u8981\u6c42\u3001\u7d0d\u671f\u3001\u898f\u5236\u3001\u30b9\u30b1\u30fc\u30eb\u3001\u30b3\u30b9\u30c8\u69cb\u9020<br \/>\n6.5 \u4eca\u5f8c\u306e\u7528\u9014\u62e1\u5927\u306e\u898b\u8fbc\u307f\u3068\u65b0\u305f\u306a\u5fdc\u7528\u9818\u57df\uff08\u304c\u3093\u30ef\u30af\u30c1\u30f3\u3001\u5e0c\u5c11\u75be\u60a3\u3001\u518d\u751f\u533b\u7642\u306a\u3069\uff09<\/strong><\/p>\n<p><strong>\u7b2c7\u7ae0\u3000\u30a8\u30f3\u30c9\u30e6\u30fc\u30b6\u30fc\u5225\u5206\u6790<\/strong><\/p>\n<p><strong>7.1 \u30a8\u30f3\u30c9\u30e6\u30fc\u30b6\u30fc\u533a\u5206<br \/>\n7.1.1 \u30d0\u30a4\u30aa\u533b\u85ac\u54c1\uff0f\u88fd\u85ac\u4f01\u696d<br \/>\n7.1.2 CDMO\uff0fCMO\uff08\u53d7\u8a17\u88fd\u9020\u6a5f\u95a2\uff09\u304a\u3088\u3073\u53d7\u8a17\u53d7\u8a17\u7814\u7a76\u6a5f\u95a2\uff08CRO\uff09<br \/>\n7.1.3 \u5b66\u8853\u7814\u7a76\u6a5f\u95a2\u304a\u3088\u3073\u30a2\u30ab\u30c7\u30df\u30a2<\/strong><\/p>\n<p><strong>7.2 \u5404\u30e6\u30fc\u30b6\u30fc\u5c64\u306e\u5e02\u5834\u9700\u8981\u3068\u4f7f\u7528\u50be\u5411<br \/>\n7.3 \u30a8\u30f3\u30c9\u30e6\u30fc\u30b6\u30fc\u5225\u6210\u9577\u4e88\u6e2c<br \/>\n7.4 \u30d1\u30fc\u30c8\u30ca\u30fc\u30b7\u30c3\u30d7\u3001\u30a2\u30a6\u30c8\u30bd\u30fc\u30b7\u30f3\u30b0\u3001\u5782\u76f4\u7d71\u5408\u306e\u52d5\u5411<\/strong><\/p>\n<p><strong>\u7b2c8\u7ae0\u3000\u5730\u57df\u5225\u5e02\u5834\u5206\u6790<\/strong><\/p>\n<p><strong>8.1 \u5730\u57df\u533a\u5206\u3068\u6982\u8981<br \/>\n8.1.1 \u5317\u7c73<br \/>\n8.1.2 \u6b27\u5dde<br \/>\n8.1.3 \u30a2\u30b8\u30a2\u592a\u5e73\u6d0b<br \/>\n8.1.4 \u30e9\u30c6\u30f3\u30a2\u30e1\u30ea\u30ab<br \/>\n8.1.5 \u4e2d\u6771\u30fb\u30a2\u30d5\u30ea\u30ab<\/strong><\/p>\n<p><strong>8.2 \u5404\u5730\u57df\u306e\u5e02\u5834\u898f\u6a21\u3068\u30b7\u30a7\u30a2\uff082024 \u5e74\uff09<br \/>\n8.3 \u5730\u57df\u5225\u306e\u6210\u9577\u4e88\u6e2c\uff082025\u20132034 \u5e74\uff09<br \/>\n8.4 \u5730\u57df\u3054\u3068\u306e\u7279\u5fb4\u3068\u6a5f\u4f1a<br \/>\n8.4.1 \u533b\u7642\u30a4\u30f3\u30d5\u30e9\u304a\u3088\u3073\u898f\u5236\u306e\u6210\u719f\u5ea6<br \/>\n8.4.2 \u4f9b\u7d66\u30c1\u30a7\u30fc\u30f3\u3068\u88fd\u9020\u62e1\u5927<br \/>\n8.4.3 \u65b0\u8208\u56fd\u3067\u306e\u6210\u9577\u30dd\u30c6\u30f3\u30b7\u30e3\u30eb<\/strong><\/p>\n<p><strong>8.5 \u5730\u57df\u5225\u306e\u8ab2\u984c\u3068\u30ea\u30b9\u30af\uff08\u898f\u5236\u3001\u4f9b\u7d66\u3001\u30b3\u30b9\u30c8\u3001\u54c1\u8cea\u7ba1\u7406\u306a\u3069\uff09<\/strong><\/p>\n<p><strong>\u7b2c9\u7ae0\u3000\u7af6\u4e89\u74b0\u5883\u3068\u4e3b\u8981\u4f01\u696d\u5206\u6790<\/strong><\/p>\n<p><strong>9.1 \u5e02\u5834\u306e\u7af6\u4e89\u69cb\u9020\u3068\u5e02\u5834\u96c6\u4e2d\u5ea6<br \/>\n9.2 \u4e3b\u8981\u4f01\u696d\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb<br \/>\n9.2.1 \u4f01\u696d\u6982\u8981<br \/>\n9.2.2 \u88fd\u54c1\u30dd\u30fc\u30c8\u30d5\u30a9\u30ea\u30aa\uff08\u539f\u6750\u6599\u30bf\u30a4\u30d7\u5225\uff09<br \/>\n9.2.3 \u5730\u57df\u5c55\u958b\u72b6\u6cc1<br \/>\n9.2.4 \u6700\u8fd1\u306e\u52d5\u5411\uff08\u63d0\u643a\u3001\u8cb7\u53ce\u3001\u6280\u8853\u958b\u767a\uff09<\/strong><\/p>\n<p><strong>9.3 \u65b0\u898f\u53c2\u5165\u4f01\u696d\u304a\u3088\u3073\u4e2d\u5c0f\u4f01\u696d\u306e\u72b6\u6cc1<br \/>\n9.4 \u4fa1\u683c\u7af6\u4e89\u3068\u5dee\u5225\u5316\u6226\u7565<br \/>\n9.5 \u30b5\u30d7\u30e9\u30a4\u30c1\u30a7\u30fc\u30f3\u6226\u7565\u3068\u4f9b\u7d66\u5b89\u5b9a\u6027<\/strong><\/p>\n<p><strong>\u7b2c10\u7ae0\u3000\u5e02\u5834\u52d5\u5411\u3001\u30c9\u30e9\u30a4\u30d0\u30fc\u304a\u3088\u3073\u30ea\u30b9\u30af\u5206\u6790<\/strong><\/p>\n<p><strong>10.1 \u5e02\u5834\u6210\u9577\u30c9\u30e9\u30a4\u30d0\u30fc<br \/>\n10.1.1 mRNA \u30ef\u30af\u30c1\u30f3\u30fb\u6cbb\u7642\u85ac\u306e\u9700\u8981\u62e1\u5927<br \/>\n10.1.2 \u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u958b\u767a\u306e\u52a0\u901f<br \/>\n10.1.3 \u898f\u5236\u30fb\u54c1\u8cea\u57fa\u6e96\u306e\u6574\u5099\u3068\u5e02\u5834\u6210\u719f<br \/>\n10.1.4 \u53d7\u8a17\u88fd\u9020\u306e\u62e1\u5927\u3068\u30a2\u30a6\u30c8\u30bd\u30fc\u30b9\u5316\u306e\u9032\u5c55<\/strong><\/p>\n<p><strong>10.2 \u5e02\u5834\u306b\u304a\u3051\u308b\u30ea\u30b9\u30af\u304a\u3088\u3073\u5236\u7d04\u8981\u56e0<br \/>\n10.2.1 \u539f\u6750\u6599\u306e\u4f9b\u7d66\u5236\u7d04\u3068\u30dc\u30c8\u30eb\u30cd\u30c3\u30af<br \/>\n10.2.2 \u9ad8\u54c1\u8cea\u30fb\u9ad8\u7d14\u5ea6\u306e\u7dad\u6301\u30b3\u30b9\u30c8<br \/>\n10.2.3 \u4fa1\u683c\u7af6\u4e89\u3068\u30b3\u30b9\u30c8\u524a\u6e1b\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc<br \/>\n10.2.4 \u9700\u8981\u5909\u52d5\u3068\u898f\u5236\u306e\u4e0d\u78ba\u5b9f\u6027<\/strong><\/p>\n<p><strong>10.3 \u5e02\u5834\u6a5f\u4f1a\u5206\u6790<br \/>\n10.3.1 \u65b0\u305f\u306a\u6cbb\u7642\u7528\u9014\uff08\u304c\u3093\u3001\u5e0c\u5c11\u75be\u60a3\u3001\u518d\u751f\u533b\u7642\u306a\u3069\uff09<br \/>\n10.3.2 \u5730\u57df\u5c55\u958b\u3068\u65b0\u8208\u56fd\u5e02\u5834\u306e\u62e1\u5927<br \/>\n10.3.3 \u30b5\u30d7\u30e9\u30a4\u30c1\u30a7\u30fc\u30f3\u5f37\u5316\u30fb\u30d0\u30c3\u30af\u30a2\u30c3\u30d7\u6226\u7565<br \/>\n10.3.4 \u9ad8\u4ed8\u52a0\u4fa1\u5024\u539f\u6750\u6599\u306e\u958b\u767a<\/strong><\/p>\n<p><strong>\u7b2c11\u7ae0\u3000\u5c06\u6765\u4e88\u6e2c\u3068\u30b7\u30ca\u30ea\u30aa\u5206\u6790<\/strong><\/p>\n<p><strong>11.1 \u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u4e88\u6e2c\uff08\u73fe\u72b6\u7dad\u6301\u30b7\u30ca\u30ea\u30aa\uff09<br \/>\n11.2 \u6210\u9577\u30b7\u30ca\u30ea\u30aa\uff08\u30ef\u30af\u30c1\u30f3\uff0f\u6cbb\u7642\u9700\u8981\u62e1\u5927\uff09<br \/>\n11.3 \u4fdd\u5b88\u30b7\u30ca\u30ea\u30aa\uff08\u9700\u8981\u920d\u5316\uff0f\u898f\u5236\u5f37\u5316\uff09<br \/>\n11.4 \u5206\u6790\u524d\u63d0\u304a\u3088\u3073\u611f\u5fdc\u5ea6\u5206\u6790<br \/>\n11.5 \u5c06\u6765\u3078\u306e\u793a\u5506\u3068\u63a8\u5968\u6226\u7565<\/strong><\/p>\n<p><strong>\u7b2c12\u7ae0\u3000\u7d50\u8ad6\u304a\u3088\u3073\u6226\u7565\u63d0\u8a00<\/strong><\/p>\n<p><strong>12.1 \u5e02\u5834\u5168\u4f53\u306e\u7dcf\u62ec<br \/>\n12.2 \u539f\u6750\u6599\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u3078\u306e\u63d0\u8a00<br \/>\n12.3 \u88fd\u85ac\u4f01\u696d\uff0fCDMO \u3078\u306e\u63d0\u8a00<br \/>\n12.4 \u653f\u7b56\u62c5\u5f53\u8005\u30fb\u898f\u5236\u5f53\u5c40\u3078\u306e\u63d0\u8a00<br \/>\n12.5 \u9577\u671f\u7684\u306a\u5e02\u5834\u6301\u7d9a\u6027\u3068\u54c1\u8cea\u4fdd\u8a3c\u3078\u306e\u63d0\u8a00<\/strong><\/p>\n<p><strong>\u4ed8\u9332\u304a\u3088\u3073\u53c2\u8003\u8cc7\u6599<\/strong><\/p>\n<p><strong>\u7528\u8a9e\u96c6\u30fb\u7565\u8a9e\u4e00\u89a7<\/strong><\/p>\n<p><strong>\u5206\u6790\u30d5\u30ec\u30fc\u30e0\u30ef\u30fc\u30af\u8a73\u7d30<\/strong><\/p>\n<p><strong>\u6b74\u53f2\u30c7\u30fc\u30bf\u8868\uff08\u904e\u53bb\u5b9f\u7e3e\uff09<\/strong><\/p>\n<p><strong>\u4e88\u6e2c\u30c7\u30fc\u30bf\u8868\uff08\u5e74\u6b21\uff0f\u30bb\u30b0\u30e1\u30f3\u30c8\u5225\uff09<\/strong><\/p>\n<p><strong>\u53c2\u8003\u6587\u732e\u4e00\u89a7<\/strong><\/p>\n<p><strong>\u30c7\u30fc\u30bf\u53ce\u96c6\u5148\u4e00\u89a7<\/strong><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p>\u203b\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u306e\u8a73\u7d30\u7d39\u4ecb\u30da\u30fc\u30b8<\/p>\n<p>\u21d2<a href=\"https:\/\/www.marketreport.jp\/mrna-synthesis-raw-materials-market\">https:\/\/www.marketreport.jp\/mrna-synthesis-raw-materials-market<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\u203b\u305d\u306e\u4ed6\u3001Grand View Research\u793e\u8abf\u67fb\u30fb\u767a\u884c\u306e\u5e02\u5834\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u4e00\u89a7<\/p>\n<p>\u21d2<a href=\"https:\/\/www.marketreport.jp\/grand-view-research-reports-list\">https:\/\/www.marketreport.jp\/grand-view-research-reports-list<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>***** H&amp;I\u30b0\u30ed\u30fc\u30d0\u30eb\u30ea\u30b5\u30fc\u30c1\uff08\u682a\uff09\u4f1a\u793e\u6982\u8981 *****<\/p>\n<p>\u30fb\u672c\u793e\u6240\u5728\u5730\uff1a\u3012104-0033 \u6771\u4eac\u90fd\u4e2d\u592e\u533a\u65b0\u5ddd1-6-12<\/p>\n<p>\u30fbTEL\uff1a03-6555-2340\u3000E-mail\uff1a<a href=\"mailto:pr@globalresearch.co.jp\">pr@globalresearch.co.jp<\/a><\/p>\n<p>\u30fb\u4e8b\u696d\u5185\u5bb9\uff1a\u5e02\u5834\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u8ca9\u58f2\u3001\u59d4\u8a17\u8abf\u67fb\u30b5\u30fc\u30d3\u30b9\u3001\u60c5\u5831\u30b3\u30f3\u30c6\u30f3\u30c4\u4f01\u753b\u3001\u7d4c\u55b6\u30b3\u30f3\u30b5\u30eb\u30c6\u30a3\u30f3\u30b0<\/p>\n<p>\u30fb\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\uff1a<a href=\"https:\/\/www.globalresearch.co.jp\">https:\/\/www.globalresearch.co.jp<\/a><\/p>\n<p>\u30fbURL\uff1a<a href=\"https:\/\/www.marketreport.jp\/mrna-synthesis-raw-materials-market\">https:\/\/www.marketreport.jp\/mrna-synthesis-raw-materials-market<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; 2025\u5e7411\u670828\u65e5 H&amp;I\u30b0\u30ed\u30fc\u30d0\u30eb\u30ea\u30b5\u30fc\u30c1\uff08\u682a\uff09 &nbsp; *****\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u7523\u696d\u8abf &hellip; <a href=\"https:\/\/www.globalresearch.co.jp\/news\/635934\/\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u7523\u696d\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u3092\u8ca9\u58f2\u958b\u59cb<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[115],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u300cmRNA\u5408\u6210\u539f\u6599\u306e\u4e16\u754c\u5e02\u5834\uff1a\u7a2e\u985e\u5225\uff08\u30ad\u30e3\u30c3\u30d7\u5264\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001\u30d7\u30e9\u30b9\u30df\u30c9DNA\u3001\u9175\u7d20\uff09\uff082025\uff5e2030\uff09\u300d\u7523\u696d\u8abf\u67fb\u30ec\u30dd\u30fc\u30c8\u3092\u8ca9\u58f2\u958b\u59cb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.globalresearch.co.jp\/news\/635934\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta 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